forum.cncdrive.com

No, you can't do math in the DROs. There is a DivideBy2 plugin here.

Verify if you can safe anything in your profile?
I mean try to change any setting save it and check if it will be like that on the next startup, because I guess that you can't save anything if the plugin enable state does not save.
And that can happen if you have your profile file or even the whole UCCNC folder write protected or the current user logged into Windows does not have the right to write to the file.

The profile file is not written if the UCCNC can't write it.
I don't know any other solutions than to have write permission to the file.
Maybe try to run the UCCNC with admin rights, I mean right click on the UCCNC icon and run as admin to see if that makes any difference.
Also you may try to install it on another folder, on another harddrive maybe. Because it is possible that you've installed it to a directory where Windows not allowing to change the files with the permissions you have.

Windows 10 by any chance?